CBX7-VPREB1 Fusion FISH Probe
The CBX7-VPREB1 Fusion FISH Probe is used to confirm a fusion of the CBX7 and VPREB1 genes. The fusion of the CBX7 and VPREB1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CBX7-VPREB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-RERE | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-REOR | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-REGO | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-REGR | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-REAQ | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-ORRE | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-OROR | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-ORGO | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-GORE | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-GOOR | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-GOGO | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-GOGR | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-GRRE | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-GROR | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-GRGO | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-GRGR | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-AQRE | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-AQOR | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-AQGO | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-AQGR | 20 (40 μL) | 200 μL |
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| CBX7-VPREB1-20-AQAQ | 20 (40 μL) | 200 μL |
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VPREB1 Gene Summary
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: V-set Pre-B Cell Surrogate Light Chain 1
Chromosome: CHR22: 22599199 -22599926
Locus: 22q11.22
CBX7 Gene Summary
This gene encodes a protein that contains the CHROMO (CHRomatin Organization MOdifier) domain. The encoded protein is a component of the Polycomb repressive complex 1 (PRC1), and is thought to control the lifespan of several normal human cells. [provided by RefSeq, Oct 2016]
Gene Name: Chromobox 7
Chromosome: CHR22: 39526778 -39548538
Locus: 22q13.1
Gene Diseases
The CBX7 VPREB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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