SEARCH OUR PRODUCT CATALOG

CBL-TRAPPC4 Fusion FISH Probe

The CBL-TRAPPC4 Fusion FISH Probe is used to confirm a fusion of the CBL and TRAPPC4 genes. The fusion of the CBL and TRAPPC4 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CBL-TRAPPC4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CBL-TRAPPC4-20-RERE 20 (40 μL) 200 μL
CBL-TRAPPC4-20-REOR 20 (40 μL) 200 μL
CBL-TRAPPC4-20-REGO 20 (40 μL) 200 μL
CBL-TRAPPC4-20-REGR 20 (40 μL) 200 μL
CBL-TRAPPC4-20-REAQ 20 (40 μL) 200 μL
CBL-TRAPPC4-20-ORRE 20 (40 μL) 200 μL
CBL-TRAPPC4-20-OROR 20 (40 μL) 200 μL
CBL-TRAPPC4-20-ORGO 20 (40 μL) 200 μL
CBL-TRAPPC4-20-ORAQ 20 (40 μL) 200 μL
CBL-TRAPPC4-20-GORE 20 (40 μL) 200 μL
CBL-TRAPPC4-20-GOOR 20 (40 μL) 200 μL
CBL-TRAPPC4-20-GOGO 20 (40 μL) 200 μL
CBL-TRAPPC4-20-GOGR 20 (40 μL) 200 μL
CBL-TRAPPC4-20-GOAQ 20 (40 μL) 200 μL
CBL-TRAPPC4-20-GRRE 20 (40 μL) 200 μL
CBL-TRAPPC4-20-GROR 20 (40 μL) 200 μL
CBL-TRAPPC4-20-GRGO 20 (40 μL) 200 μL
CBL-TRAPPC4-20-GRGR 20 (40 μL) 200 μL
CBL-TRAPPC4-20-GRAQ 20 (40 μL) 200 μL
CBL-TRAPPC4-20-AQRE 20 (40 μL) 200 μL
CBL-TRAPPC4-20-AQOR 20 (40 μL) 200 μL
CBL-TRAPPC4-20-AQGO 20 (40 μL) 200 μL
CBL-TRAPPC4-20-AQGR 20 (40 μL) 200 μL
CBL-TRAPPC4-20-AQAQ 20 (40 μL) 200 μL

CBL Gene Summary

This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Jul 2016]

Gene Name: Cbl Proto-oncogene

Chromosome: CHR11: 119076989 -119178859

Locus: 11q23.3

TRAPPC4 Gene Summary

The Trafficking Protein Particle Complex 4 (TRAPPC4) gene is located on chr11 :118889240-118894385 at 11q23.3.

Gene Name: Trafficking Protein Particle Complex 4

Chromosome: CHR11: 118889240 -118894385

Locus: 11q23.3

Gene Diseases

The CBL TRAPPC4 Fusion has been associated with the following diseases:

Disease Name
Esophageal Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.