CASZ1-MASP2 Fusion FISH Probe
The CASZ1-MASP2 Fusion FISH Probe is used to confirm a fusion of the CASZ1 and MASP2 genes. The fusion of the CASZ1 and MASP2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CASZ1-MASP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-RERE | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-REOR | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-REGO | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-REGR | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-REAQ | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-ORRE | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-OROR | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-ORGO | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-GORE | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-GOOR | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-GOGO | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-GOGR | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-GRRE | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-GROR | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-GRGO | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-GRGR | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-AQRE | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-AQOR | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-AQGO | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-AQGR | 20 (40 μL) | 200 μL |
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| CASZ1-MASP2-20-AQAQ | 20 (40 μL) | 200 μL |
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MASP2 Gene Summary
This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Gene Name: Mannan Binding Lectin Serine Peptidase 2
Chromosome: CHR1: 11086579 -11107296
Locus: 1p36.22
CASZ1 Gene Summary
The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Gene Name: Castor Zinc Finger 1
Chromosome: CHR1: 10696665 -10856707
Locus: 1p36.22
Gene Diseases
The CASZ1 MASP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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