CAST-CDHR3 Fusion FISH Probe
The CAST-CDHR3 Fusion FISH Probe is used to confirm a fusion of the CAST and CDHR3 genes. The fusion of the CAST and CDHR3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CAST-CDHR3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-RERE | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-REOR | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-REGO | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-REGR | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-REAQ | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-ORRE | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-OROR | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-ORGO | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-GORE | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-GOOR | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-GOGO | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-GOGR | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-GRRE | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-GROR | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-GRGO | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-GRGR | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-AQRE | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-AQOR | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-AQGO | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-AQGR | 20 (40 μL) | 200 μL |
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| CAST-CDHR3-20-AQAQ | 20 (40 μL) | 200 μL |
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CAST Gene Summary
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Gene Name: Calpastatin
Chromosome: CHR5: 95997740 -96110385
Locus: 5q15
CDHR3 Gene Summary
The Cadherin Related Family Member 3 (CDHR3) gene is located on chr7 :105603656-105676877 at 7q22.3.
Gene Name: Cadherin Related Family Member 3
Chromosome: CHR7: 105603656 -105676877
Locus: 7q22.3
Gene Diseases
The CAST CDHR3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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