CASP7-LRRC27 Fusion FISH Probe
The CASP7-LRRC27 Fusion FISH Probe is used to confirm a fusion of the CASP7 and LRRC27 genes. The fusion of the CASP7 and LRRC27 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CASP7-LRRC27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-RERE | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-REOR | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-REGO | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-REGR | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-REAQ | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-ORRE | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-OROR | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-ORGO | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-ORAQ | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-GORE | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-GOOR | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-GOGO | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-GOGR | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-GOAQ | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-GRRE | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-GROR | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-GRGO | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-GRGR | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-GRAQ | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-AQRE | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-AQOR | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-AQGO | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-AQGR | 20 (40 μL) | 200 μL |
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| CASP7-LRRC27-20-AQAQ | 20 (40 μL) | 200 μL |
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CASP7 Gene Summary
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Name: Caspase 7
Chromosome: CHR10: 115438934 -115490664
Locus: 10q25.3
LRRC27 Gene Summary
The Leucine Rich Repeat Containing 27 (LRRC27) gene is located on chr10 :134145613-134195010 at 10q26.3.
Gene Name: Leucine Rich Repeat Containing 27
Chromosome: CHR10: 134145613 -134195010
Locus: 10q26.3
Gene Diseases
The CASP7 LRRC27 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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