CARM1-PLA2G4C Fusion FISH Probe
The CARM1-PLA2G4C Fusion FISH Probe is used to confirm a fusion of the CARM1 and PLA2G4C genes. The fusion of the CARM1 and PLA2G4C genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CARM1-PLA2G4C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-RERE | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-REOR | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-REGO | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-REGR | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-REAQ | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-ORRE | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-OROR | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-ORGO | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-ORAQ | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-GORE | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-GOOR | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-GOGO | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-GOGR | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-GOAQ | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-GRRE | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-GROR | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-GRGO | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-GRGR | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-GRAQ | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-AQRE | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-AQOR | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-AQGO | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-AQGR | 20 (40 μL) | 200 μL |
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| CARM1-PLA2G4C-20-AQAQ | 20 (40 μL) | 200 μL |
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PLA2G4C Gene Summary
This gene encodes a protein which is a member of the phospholipase A2 enzyme family which hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules. The encoded protein has been shown to be a calcium-independent and membrane bound enzyme. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
Gene Name: Phospholipase A2 Group IVC
Chromosome: CHR19: 48551099 -48614109
Locus: 19q13.33
CARM1 Gene Summary
This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. [provided by RefSeq, Aug 2013]
Gene Name: Coactivator Associated Arginine Methyltransferase 1
Chromosome: CHR19: 10982252 -11033448
Locus: 19p13.2
Gene Diseases
The CARM1 PLA2G4C Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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