CARM1-KLF11 Fusion FISH Probe
The CARM1-KLF11 Fusion FISH Probe is used to confirm a fusion of the CARM1 and KLF11 genes. The fusion of the CARM1 and KLF11 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CARM1-KLF11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-RERE | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-REOR | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-REGO | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-REGR | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-REAQ | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-ORRE | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-OROR | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-ORGO | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-ORAQ | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-GORE | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-GOOR | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-GOGO | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-GOGR | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-GOAQ | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-GRRE | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-GROR | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-GRGO | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-GRGR | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-GRAQ | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-AQRE | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-AQOR | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-AQGO | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-AQGR | 20 (40 μL) | 200 μL |
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| CARM1-KLF11-20-AQAQ | 20 (40 μL) | 200 μL |
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KLF11 Gene Summary
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Gene Name: Kruppel Like Factor 11
Chromosome: CHR2: 10183681 -10194963
Locus: 2p25.1
CARM1 Gene Summary
This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. [provided by RefSeq, Aug 2013]
Gene Name: Coactivator Associated Arginine Methyltransferase 1
Chromosome: CHR19: 10982252 -11033448
Locus: 19p13.2
Gene Diseases
The CARM1 KLF11 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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