CARM1-CASP14 Fusion FISH Probe
The CARM1-CASP14 Fusion FISH Probe is used to confirm a fusion of the CARM1 and CASP14 genes. The fusion of the CARM1 and CASP14 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CARM1-CASP14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-RERE | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-REOR | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-REGO | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-REGR | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-REAQ | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-ORRE | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-OROR | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-ORGO | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-ORAQ | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-GORE | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-GOOR | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-GOGO | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-GOGR | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-GOAQ | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-GRRE | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-GROR | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-GRGO | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-GRGR | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-GRAQ | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-AQRE | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-AQOR | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-AQGO | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-AQGR | 20 (40 μL) | 200 μL |
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| CARM1-CASP14-20-AQAQ | 20 (40 μL) | 200 μL |
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CARM1 Gene Summary
This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. [provided by RefSeq, Aug 2013]
Gene Name: Coactivator Associated Arginine Methyltransferase 1
Chromosome: CHR19: 10982252 -11033448
Locus: 19p13.2
CASP14 Gene Summary
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]
Gene Name: Caspase 14
Chromosome: CHR19: 15160290 -15169103
Locus: 19p13.12
Gene Diseases
The CARM1 CASP14 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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