CARD11-ZNRD1 Fusion FISH Probe
The CARD11-ZNRD1 Fusion FISH Probe is used to confirm a fusion of the CARD11 and ZNRD1 genes. The fusion of the CARD11 and ZNRD1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CARD11-ZNRD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-RERE | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-REOR | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-REGO | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-REGR | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-REAQ | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-ORRE | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-OROR | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-ORGO | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-GORE | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-GOOR | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-GOGO | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-GOGR | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-GRRE | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-GROR | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-GRGO | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-GRGR | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-AQRE | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-AQOR | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-AQGO | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-AQGR | 20 (40 μL) | 200 μL |
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| CARD11-ZNRD1-20-AQAQ | 20 (40 μL) | 200 μL |
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ZNRD1 Gene Summary
This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Zinc Ribbon Domain Containing 1
Chromosome: CHR6: 30029035 -30032686
Locus: 6p22.1
CARD11 Gene Summary
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
Gene Name: Caspase Recruitment Domain Family Member 11
Chromosome: CHR7: 2945709 -3083509
Locus: 7p22.2
Gene Diseases
The CARD11 ZNRD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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