CAPZB-TMCO4 Fusion FISH Probe
The CAPZB-TMCO4 Fusion FISH Probe is used to confirm a fusion of the CAPZB and TMCO4 genes. The fusion of the CAPZB and TMCO4 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CAPZB-TMCO4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-RERE | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-REOR | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-REGO | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-REGR | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-REAQ | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-ORRE | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-OROR | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-ORGO | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-ORAQ | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-GORE | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-GOOR | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-GOGO | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-GOGR | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-GOAQ | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-GRRE | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-GROR | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-GRGO | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-GRGR | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-GRAQ | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-AQRE | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-AQOR | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-AQGO | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-AQGR | 20 (40 μL) | 200 μL |
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| CAPZB-TMCO4-20-AQAQ | 20 (40 μL) | 200 μL |
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CAPZB Gene Summary
This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. A pseudogene of this gene is located on the long arm of chromosome 2. Multiple alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, Aug 2013]
Gene Name: Capping Actin Protein Of Muscle Z-line Beta Subunit
Chromosome: CHR1: 19665266 -19812066
Locus: 1p36.13
TMCO4 Gene Summary
The Transmembrane And Coiled-coil Domains 4 (TMCO4) gene is located on chr1 :20008705-20126410 at 1p36.13.
Gene Name: Transmembrane And Coiled-coil Domains 4
Chromosome: CHR1: 20008705 -20126410
Locus: 1p36.13
Gene Diseases
The CAPZB TMCO4 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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