CAPZA1-MIER1 Fusion FISH Probe
The CAPZA1-MIER1 Fusion FISH Probe is used to confirm a fusion of the CAPZA1 and MIER1 genes. The fusion of the CAPZA1 and MIER1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CAPZA1-MIER1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-RERE | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-REOR | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-REGO | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-REGR | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-REAQ | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-ORRE | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-OROR | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-ORGO | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-GORE | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-GOOR | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-GOGO | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-GOGR | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-GRRE | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-GROR | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-GRGO | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-GRGR | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-AQRE | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-AQOR | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-AQGO | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-AQGR | 20 (40 μL) | 200 μL |
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| CAPZA1-MIER1-20-AQAQ | 20 (40 μL) | 200 μL |
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CAPZA1 Gene Summary
CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq, Jul 2008]
Gene Name: Capping Actin Protein Of Muscle Z-line Alpha Subunit 1
Chromosome: CHR1: 113162074 -113214241
Locus: 1p13.2
MIER1 Gene Summary
This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. [provided by RefSeq, May 2013]
Gene Name: MIER1 Transcriptional Regulator
Chromosome: CHR1: 67390577 -67454302
Locus: 1p31.3
Gene Diseases
The CAPZA1 MIER1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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