CAPN5-HSD17B14 Fusion FISH Probe
The CAPN5-HSD17B14 Fusion FISH Probe is used to confirm a fusion of the CAPN5 and HSD17B14 genes. The fusion of the CAPN5 and HSD17B14 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CAPN5-HSD17B14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-RERE | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-REOR | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-REGO | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-REGR | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-REAQ | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-ORRE | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-OROR | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-ORGO | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-ORAQ | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-GORE | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-GOOR | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-GOGO | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-GOGR | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-GOAQ | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-GRRE | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-GROR | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-GRGO | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-GRGR | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-GRAQ | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-AQRE | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-AQOR | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-AQGO | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-AQGR | 20 (40 μL) | 200 μL |
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| CAPN5-HSD17B14-20-AQAQ | 20 (40 μL) | 200 μL |
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CAPN5 Gene Summary
Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008]
Gene Name: Calpain 5
Chromosome: CHR11: 76777991 -76837198
Locus: 11q13.5
HSD17B14 Gene Summary
17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]
Gene Name: Hydroxysteroid 17-beta Dehydrogenase 14
Chromosome: CHR19: 49316273 -49339934
Locus: 19q13.33
Gene Diseases
The CAPN5 HSD17B14 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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