CANX-PLAT Fusion FISH Probe
The CANX-PLAT Fusion FISH Probe is used to confirm a fusion of the CANX and PLAT genes. The fusion of the CANX and PLAT genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CANX-PLAT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CANX-PLAT-20-AQAQ | 20 (40 μL) | 200 μL |
|
CANX Gene Summary
This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Gene Name: Calnexin
Chromosome: CHR5: 179125929 -179158639
Locus: 5q35.3
PLAT Gene Summary
This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Name: Plasminogen Activator, Tissue Type
Chromosome: CHR8: 42032235 -42065194
Locus: 8p11.21
Gene Diseases
The CANX PLAT Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|