CAND1-TUSC5 Fusion FISH Probe
The CAND1-TUSC5 Fusion FISH Probe is used to confirm a fusion of the CAND1 and TUSC5 genes. The fusion of the CAND1 and TUSC5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CAND1-TUSC5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-RERE | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-REOR | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-REGO | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-REGR | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-REAQ | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-ORRE | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-OROR | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-ORGO | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-ORAQ | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-GORE | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-GOOR | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-GOGO | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-GOGR | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-GOAQ | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-GRRE | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-GROR | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-GRGO | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-GRGR | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-GRAQ | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-AQRE | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-AQOR | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-AQGO | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-AQGR | 20 (40 μL) | 200 μL |
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| CAND1-TUSC5-20-AQAQ | 20 (40 μL) | 200 μL |
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CAND1 Gene Summary
This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Gene Name: Cullin Associated And Neddylation Dissociated 1
Chromosome: CHR12: 67663060 -67708388
Locus: 12q14.3-q15
TUSC5 Gene Summary
The Tumor Suppressor Candidate 5 (TUSC5) gene is located on chr17 :1182956-1204281 at 17p13.3.
Gene Name: Tumor Suppressor Candidate 5
Chromosome: CHR17: 1182956 -1204281
Locus: 17p13.3
Gene Diseases
The CAND1 TUSC5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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