CAMTA1-DHRS3 Fusion FISH Probe
The CAMTA1-DHRS3 Fusion FISH Probe is used to confirm a fusion of the CAMTA1 and DHRS3 genes. The fusion of the CAMTA1 and DHRS3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CAMTA1-DHRS3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-RERE | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-REOR | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-REGO | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-REGR | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-REAQ | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-ORRE | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-OROR | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-ORGO | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-GORE | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-GOOR | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-GOGO | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-GOGR | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-GRRE | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-GROR | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-GRGO | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-GRGR | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-AQRE | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-AQOR | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-AQGO | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-AQGR | 20 (40 μL) | 200 μL |
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| CAMTA1-DHRS3-20-AQAQ | 20 (40 μL) | 200 μL |
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DHRS3 Gene Summary
Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]
Gene Name: Dehydrogenase/reductase 3
Chromosome: CHR1: 12627938 -12677820
Locus: 1p36.21
CAMTA1 Gene Summary
The protein encoded by this gene contains a CG1 DNA-binding domain, a transcription factor immunoglobulin domain, ankyrin repeats, and calmodulin-binding IQ motifs. The encoded protein is thought to be a transcription factor and may be a tumor suppressor. However, a translocation event is sometimes observed between this gene and the WWTR1 gene, with the resulting WWTR1-CAMTA1 oncoprotein leading to epithelioid hemangioendothelioma, a malignant vascular cancer. [provided by RefSeq, Mar 2017]
Gene Name: Calmodulin Binding Transcription Activator 1
Chromosome: CHR1: 6845383 -7829766
Locus: 1p36.31-p36.23
Gene Diseases
The CAMTA1 DHRS3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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