CADPS-FAM19A1 Fusion FISH Probe
The CADPS-FAM19A1 Fusion FISH Probe is used to confirm a fusion of the CADPS and FAM19A1 genes. The fusion of the CADPS and FAM19A1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CADPS-FAM19A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-RERE | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-REOR | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-REGO | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-REGR | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-REAQ | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-ORRE | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-OROR | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-ORGO | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-GORE | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-GOOR | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-GOGO | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-GOGR | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-GRRE | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-GROR | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-GRGO | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-GRGR | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-AQRE | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-AQOR | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-AQGO | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-AQGR | 20 (40 μL) | 200 μL |
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| CADPS-FAM19A1-20-AQAQ | 20 (40 μL) | 200 μL |
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CADPS Gene Summary
This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008]
Gene Name: Calcium Dependent Secretion Activator
Chromosome: CHR3: 62384020 -62861064
Locus: 3p14.2
FAM19A1 Gene Summary
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]
Gene Name: Family With Sequence Similarity 19 Member A1, C-C Motif Chemokine Like
Chromosome: CHR3: 68053453 -68594771
Locus: 3p14.1
Gene Diseases
The CADPS FAM19A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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