CACNB1-KRT40 Fusion FISH Probe
The CACNB1-KRT40 Fusion FISH Probe is used to confirm a fusion of the CACNB1 and KRT40 genes. The fusion of the CACNB1 and KRT40 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CACNB1-KRT40-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-RERE | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-REOR | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-REGO | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-REGR | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-REAQ | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-ORRE | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-OROR | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-ORGO | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-ORAQ | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-GORE | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-GOOR | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-GOGO | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-GOGR | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-GOAQ | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-GRRE | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-GROR | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-GRGO | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-GRGR | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-GRAQ | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-AQRE | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-AQOR | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-AQGO | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-AQGR | 20 (40 μL) | 200 μL |
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| CACNB1-KRT40-20-AQAQ | 20 (40 μL) | 200 μL |
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CACNB1 Gene Summary
The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Calcium Voltage-gated Channel Auxiliary Subunit Beta 1
Chromosome: CHR17: 37329708 -37353901
Locus: 17q12
KRT40 Gene Summary
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
Gene Name: Keratin 40
Chromosome: CHR17: 39133967 -39143387
Locus: 17q21.2
Gene Diseases
The CACNB1 KRT40 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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