CACHD1-ROR1 Fusion FISH Probe
The CACHD1-ROR1 Fusion FISH Probe is used to confirm a fusion of the CACHD1 and ROR1 genes. The fusion of the CACHD1 and ROR1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CACHD1-ROR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-RERE | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-REOR | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-REGO | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-REGR | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-REAQ | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-ORRE | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-OROR | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-ORGO | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-GORE | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-GOOR | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-GOGO | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-GOGR | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-GRRE | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-GROR | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-GRGO | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-GRGR | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-AQRE | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-AQOR | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-AQGO | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-AQGR | 20 (40 μL) | 200 μL |
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| CACHD1-ROR1-20-AQAQ | 20 (40 μL) | 200 μL |
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ROR1 Gene Summary
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
Gene Name: Receptor Tyrosine Kinase Like Orphan Receptor 1
Chromosome: CHR1: 64239689 -64644707
Locus: 1p31.3
CACHD1 Gene Summary
The Cache Domain Containing 1 (CACHD1) gene is located on chr1 :64936475-65158741 at 1p31.3.
Gene Name: Cache Domain Containing 1
Chromosome: CHR1: 64936475 -65158741
Locus: 1p31.3
Gene Diseases
The CACHD1 ROR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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