CABIN1-GRIN2A Fusion FISH Probe
The CABIN1-GRIN2A Fusion FISH Probe is used to confirm a fusion of the CABIN1 and GRIN2A genes. The fusion of the CABIN1 and GRIN2A genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CABIN1-GRIN2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-RERE | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-REOR | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-REGO | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-REGR | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-REAQ | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-ORRE | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-OROR | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-ORGO | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-GORE | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-GOOR | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-GOGO | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-GOGR | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-GRRE | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-GROR | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-GRGO | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-GRGR | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-AQRE | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-AQOR | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-AQGO | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-AQGR | 20 (40 μL) | 200 μL |
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| CABIN1-GRIN2A-20-AQAQ | 20 (40 μL) | 200 μL |
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GRIN2A Gene Summary
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: Glutamate Ionotropic Receptor NMDA Type Subunit 2A
Chromosome: CHR16: 9847264 -10276611
Locus: 16p13.2
CABIN1 Gene Summary
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]
Gene Name: Calcineurin Binding Protein 1
Chromosome: CHR22: 24407764 -24574596
Locus: 22q11.23
Gene Diseases
The CABIN1 GRIN2A Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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