C7ORF44-GCK Fusion FISH Probe
The C7ORF44-GCK Fusion FISH Probe is used to confirm a fusion of the C7ORF44 and GCK genes. The fusion of the C7ORF44 and GCK genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| C7ORF44-GCK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-RERE | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-REOR | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-REGO | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-REGR | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-OROR | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-GORE | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-GROR | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| C7ORF44-GCK-20-AQAQ | 20 (40 μL) | 200 μL |
|
GCK Gene Summary
This gene encodes a member of the hexokinase family of proteins. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. The use of multiple promoters and alternative splicing of this gene result in distinct protein isoforms that exhibit tissue-specific expression in the pancreas and liver. In the pancreas, this enzyme plays a role in glucose-stimulated insulin secretion, while in the liver, this enzyme is important in glucose uptake and conversion to glycogen. Mutations in this gene that alter enzyme activity have been associated with multiple types of diabetes and hyperinsulinemic hypoglycemia. [provided by RefSeq, Aug 2017]
Gene Name: Glucokinase
Chromosome: CHR7: 44183869 -44229022
Locus: 7p13
Gene Diseases
The C7ORF44 GCK Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|