C7ORF36-ALS2 Fusion FISH Probe
The C7ORF36-ALS2 Fusion FISH Probe is used to confirm a fusion of the C7ORF36 and ALS2 genes. The fusion of the C7ORF36 and ALS2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C7ORF36-ALS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-RERE | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-REOR | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-REGO | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-REGR | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-REAQ | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-ORRE | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-OROR | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-ORGO | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-GORE | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-GOOR | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-GOGO | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-GOGR | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-GRRE | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-GROR | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-GRGO | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-GRGR | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-AQRE | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-AQOR | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-AQGO | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-AQGR | 20 (40 μL) | 200 μL |
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| C7ORF36-ALS2-20-AQAQ | 20 (40 μL) | 200 μL |
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ALS2 Gene Summary
The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Gene Name: ALS2, Alsin Rho Guanine Nucleotide Exchange Factor
Chromosome: CHR2: 202564985 -202645895
Locus: 2q33.1
Gene Diseases
The C7ORF36 ALS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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