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C6ORF204-ROS1 Fusion FISH Probe

The C6ORF204-ROS1 Fusion FISH Probe is used to confirm a fusion of the C6ORF204 and ROS1 genes. The fusion of the C6ORF204 and ROS1 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
C6ORF204-ROS1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
C6ORF204-ROS1-20-RERE 20 (40 μL) 200 μL
C6ORF204-ROS1-20-REOR 20 (40 μL) 200 μL
C6ORF204-ROS1-20-REGO 20 (40 μL) 200 μL
C6ORF204-ROS1-20-REGR 20 (40 μL) 200 μL
C6ORF204-ROS1-20-REAQ 20 (40 μL) 200 μL
C6ORF204-ROS1-20-ORRE 20 (40 μL) 200 μL
C6ORF204-ROS1-20-OROR 20 (40 μL) 200 μL
C6ORF204-ROS1-20-ORGO 20 (40 μL) 200 μL
C6ORF204-ROS1-20-ORAQ 20 (40 μL) 200 μL
C6ORF204-ROS1-20-GORE 20 (40 μL) 200 μL
C6ORF204-ROS1-20-GOOR 20 (40 μL) 200 μL
C6ORF204-ROS1-20-GOGO 20 (40 μL) 200 μL
C6ORF204-ROS1-20-GOGR 20 (40 μL) 200 μL
C6ORF204-ROS1-20-GOAQ 20 (40 μL) 200 μL
C6ORF204-ROS1-20-GRRE 20 (40 μL) 200 μL
C6ORF204-ROS1-20-GROR 20 (40 μL) 200 μL
C6ORF204-ROS1-20-GRGO 20 (40 μL) 200 μL
C6ORF204-ROS1-20-GRGR 20 (40 μL) 200 μL
C6ORF204-ROS1-20-GRAQ 20 (40 μL) 200 μL
C6ORF204-ROS1-20-AQRE 20 (40 μL) 200 μL
C6ORF204-ROS1-20-AQOR 20 (40 μL) 200 μL
C6ORF204-ROS1-20-AQGO 20 (40 μL) 200 μL
C6ORF204-ROS1-20-AQGR 20 (40 μL) 200 μL
C6ORF204-ROS1-20-AQAQ 20 (40 μL) 200 μL

ROS1 Gene Summary

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]

Gene Name: ROS Proto-oncogene 1, Receptor Tyrosine Kinase

Chromosome: CHR6: 117609529 -117747018

Locus: 6q22.1

Gene Diseases

The C6ORF204 ROS1 Fusion has been associated with the following diseases:

Disease Name
Glioblastoma Multiforme

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Comprehensive Genomic Profiling of Malignant Effusions in Patients with Metastatic Lung Adenocarcinoma

In this study, the utility of performing targeted next-generation sequencing (NGS) on malignant effusions from patients with metastatic lung adenocarcinoma was investigated. NGS is a high throughput technology, which utilizes a small sample input, but the suitability of NGS analysis for tissue-free cytology samples such as malignant body fluids is not well understood. In order to investigate the adequacy of NGS on liquid biopsies of MLA, targeted NGS was performed using custom target panels consisting of many oncogenes. Additional non-NGS molecular tests were performed on the effusion samples, including fluorescence in situ hybridization (FISH) analysis for the oncogene ROS1, using a break-apart FISH probe manufactured by Empire Genomics.