C3ORF72-PROS1 Fusion FISH Probe
The C3ORF72-PROS1 Fusion FISH Probe is used to confirm a fusion of the C3ORF72 and PROS1 genes. The fusion of the C3ORF72 and PROS1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C3ORF72-PROS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-RERE | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-REOR | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-REGO | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-REGR | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-REAQ | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-ORRE | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-OROR | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-ORGO | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-GORE | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-GOOR | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-GOGO | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-GOGR | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-GRRE | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-GROR | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-GRGO | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-GRGR | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-AQRE | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-AQOR | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-AQGO | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-AQGR | 20 (40 μL) | 200 μL |
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| C3ORF72-PROS1-20-AQAQ | 20 (40 μL) | 200 μL |
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PROS1 Gene Summary
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015]
Gene Name: Protein S
Chromosome: CHR3: 93591880 -93692934
Locus: 3q11.1
Gene Diseases
The C3ORF72 PROS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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