C3ORF52-CD86 Fusion FISH Probe
The C3ORF52-CD86 Fusion FISH Probe is used to confirm a fusion of the C3ORF52 and CD86 genes. The fusion of the C3ORF52 and CD86 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C3ORF52-CD86-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-RERE | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-REOR | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-REGO | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-REGR | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-REAQ | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-ORRE | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-OROR | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-ORGO | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-ORAQ | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-GORE | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-GOOR | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-GOGO | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-GOGR | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-GOAQ | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-GRRE | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-GROR | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-GRGO | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-GRGR | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-GRAQ | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-AQRE | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-AQOR | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-AQGO | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-AQGR | 20 (40 μL) | 200 μL |
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| C3ORF52-CD86-20-AQAQ | 20 (40 μL) | 200 μL |
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CD86 Gene Summary
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Gene Name: CD86 Molecule
Chromosome: CHR3: 121774208 -121839988
Locus: 3q13.33
C3orf52 Gene Summary
The Chromosome 3 Open Reading Frame 52 (C3orf52) gene is located on chr3 :111805181-111837073 at 3q13.2.
Gene Name: Chromosome 3 Open Reading Frame 52
Chromosome: CHR3: 111805181 -111837073
Locus: 3q13.2
Gene Diseases
The C3ORF52 CD86 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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