C3-MFN1 Fusion FISH Probe
The C3-MFN1 Fusion FISH Probe is used to confirm a fusion of the C3 and MFN1 genes. The fusion of the C3 and MFN1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C3-MFN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-RERE | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-REOR | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-REGO | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-REGR | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-REAQ | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-ORRE | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-OROR | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-ORGO | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-GORE | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-GOOR | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-GOGO | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-GOGR | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-GRRE | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-GROR | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-GRGO | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-GRGR | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-AQRE | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-AQOR | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-AQGO | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-AQGR | 20 (40 μL) | 200 μL |
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| C3-MFN1-20-AQAQ | 20 (40 μL) | 200 μL |
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C3 Gene Summary
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
Gene Name: Complement C3
Chromosome: CHR19: 6677845 -6720662
Locus: 19p13.3
MFN1 Gene Summary
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq, Jul 2008]
Gene Name: Mitofusin 1
Chromosome: CHR3: 179065479 -179111008
Locus: 3q26.33
Gene Diseases
The C3 MFN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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