C3-ABCF1 Fusion FISH Probe
The C3-ABCF1 Fusion FISH Probe is used to confirm a fusion of the C3 and ABCF1 genes. The fusion of the C3 and ABCF1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C3-ABCF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-RERE | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-REOR | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-REGO | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-REGR | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-REAQ | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-ORRE | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-OROR | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-ORGO | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-GORE | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-GOOR | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-GOGO | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-GOGR | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-GRRE | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-GROR | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-GRGO | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-GRGR | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-AQRE | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-AQOR | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-AQGO | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-AQGR | 20 (40 μL) | 200 μL |
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| C3-ABCF1-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCF1 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily F Member 1
Chromosome: CHR6: 30539169 -30559309
Locus: 6p21.33
C3 Gene Summary
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
Gene Name: Complement C3
Chromosome: CHR19: 6677845 -6720662
Locus: 19p13.3
Gene Diseases
The C3 ABCF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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