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C2CD3-VPS37C Fusion FISH Probe

The C2CD3-VPS37C Fusion FISH Probe is used to confirm a fusion of the C2CD3 and VPS37C genes. The fusion of the C2CD3 and VPS37C genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
C2CD3-VPS37C-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
C2CD3-VPS37C-20-RERE 20 (40 μL) 200 μL
C2CD3-VPS37C-20-REOR 20 (40 μL) 200 μL
C2CD3-VPS37C-20-REGO 20 (40 μL) 200 μL
C2CD3-VPS37C-20-REGR 20 (40 μL) 200 μL
C2CD3-VPS37C-20-REAQ 20 (40 μL) 200 μL
C2CD3-VPS37C-20-ORRE 20 (40 μL) 200 μL
C2CD3-VPS37C-20-OROR 20 (40 μL) 200 μL
C2CD3-VPS37C-20-ORGO 20 (40 μL) 200 μL
C2CD3-VPS37C-20-ORAQ 20 (40 μL) 200 μL
C2CD3-VPS37C-20-GORE 20 (40 μL) 200 μL
C2CD3-VPS37C-20-GOOR 20 (40 μL) 200 μL
C2CD3-VPS37C-20-GOGO 20 (40 μL) 200 μL
C2CD3-VPS37C-20-GOGR 20 (40 μL) 200 μL
C2CD3-VPS37C-20-GOAQ 20 (40 μL) 200 μL
C2CD3-VPS37C-20-GRRE 20 (40 μL) 200 μL
C2CD3-VPS37C-20-GROR 20 (40 μL) 200 μL
C2CD3-VPS37C-20-GRGO 20 (40 μL) 200 μL
C2CD3-VPS37C-20-GRGR 20 (40 μL) 200 μL
C2CD3-VPS37C-20-GRAQ 20 (40 μL) 200 μL
C2CD3-VPS37C-20-AQRE 20 (40 μL) 200 μL
C2CD3-VPS37C-20-AQOR 20 (40 μL) 200 μL
C2CD3-VPS37C-20-AQGO 20 (40 μL) 200 μL
C2CD3-VPS37C-20-AQGR 20 (40 μL) 200 μL
C2CD3-VPS37C-20-AQAQ 20 (40 μL) 200 μL

C2CD3 Gene Summary

This gene encodes a protein that functions as a regulator of centriole elongation. Studies of the orthologous mouse protein show that it promotes centriolar distal appendage assembly and is also required for the recruitment of other ciliogenic proteins, including intraflagellar transport proteins. Mutations in this gene cause orofaciodigital syndrome XIV (OFD14), a ciliopathy resulting in malformations of the oral cavity, face and digits. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Gene Name: C2 Calcium Dependent Domain Containing 3

Chromosome: CHR11: 73745479 -73882064

Locus: 11q13.4

VPS37C Gene Summary

VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]

Gene Name: VPS37C, ESCRT-I Subunit

Chromosome: CHR11: 60897727 -60928916

Locus: 11q12.2

Gene Diseases

The C2CD3 VPS37C Fusion has been associated with the following diseases:

Disease Name
Rectum Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.