C2CD3-P2RY6 Fusion FISH Probe
The C2CD3-P2RY6 Fusion FISH Probe is used to confirm a fusion of the C2CD3 and P2RY6 genes. The fusion of the C2CD3 and P2RY6 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C2CD3-P2RY6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-RERE | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-REOR | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-REGO | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-REGR | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-REAQ | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-ORRE | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-OROR | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-ORGO | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-ORAQ | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-GORE | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-GOOR | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-GOGO | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-GOGR | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-GOAQ | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-GRRE | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-GROR | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-GRGO | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-GRGR | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-GRAQ | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-AQRE | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-AQOR | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-AQGO | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-AQGR | 20 (40 μL) | 200 μL |
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| C2CD3-P2RY6-20-AQAQ | 20 (40 μL) | 200 μL |
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P2RY6 Gene Summary
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Mar 2013]
Gene Name: Pyrimidinergic Receptor P2Y6
Chromosome: CHR11: 72975569 -73008850
Locus: 11q13.4
C2CD3 Gene Summary
This gene encodes a protein that functions as a regulator of centriole elongation. Studies of the orthologous mouse protein show that it promotes centriolar distal appendage assembly and is also required for the recruitment of other ciliogenic proteins, including intraflagellar transport proteins. Mutations in this gene cause orofaciodigital syndrome XIV (OFD14), a ciliopathy resulting in malformations of the oral cavity, face and digits. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Name: C2 Calcium Dependent Domain Containing 3
Chromosome: CHR11: 73745479 -73882064
Locus: 11q13.4
Gene Diseases
The C2CD3 P2RY6 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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