C2CD3-NCAM1 Fusion FISH Probe
The C2CD3-NCAM1 Fusion FISH Probe is used to confirm a fusion of the C2CD3 and NCAM1 genes. The fusion of the C2CD3 and NCAM1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C2CD3-NCAM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-RERE | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-REOR | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-REGO | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-REGR | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-REAQ | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-ORRE | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-OROR | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-ORGO | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-GORE | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-GOOR | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-GOGO | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-GOGR | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-GRRE | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-GROR | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-GRGO | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-GRGR | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-AQRE | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-AQOR | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-AQGO | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-AQGR | 20 (40 μL) | 200 μL |
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| C2CD3-NCAM1-20-AQAQ | 20 (40 μL) | 200 μL |
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NCAM1 Gene Summary
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Gene Name: Neural Cell Adhesion Molecule 1
Chromosome: CHR11: 112831968 -113149158
Locus: 11q23.2
C2CD3 Gene Summary
This gene encodes a protein that functions as a regulator of centriole elongation. Studies of the orthologous mouse protein show that it promotes centriolar distal appendage assembly and is also required for the recruitment of other ciliogenic proteins, including intraflagellar transport proteins. Mutations in this gene cause orofaciodigital syndrome XIV (OFD14), a ciliopathy resulting in malformations of the oral cavity, face and digits. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Name: C2 Calcium Dependent Domain Containing 3
Chromosome: CHR11: 73745479 -73882064
Locus: 11q13.4
Gene Diseases
The C2CD3 NCAM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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