C2CD2L-DDX10 Fusion FISH Probe
The C2CD2L-DDX10 Fusion FISH Probe is used to confirm a fusion of the C2CD2L and DDX10 genes. The fusion of the C2CD2L and DDX10 genes has been associated with Acute Myeloid Leukemia. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C2CD2L-DDX10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-RERE | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-REOR | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-REGO | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-REGR | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-REAQ | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-ORRE | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-OROR | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-ORGO | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-ORAQ | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-GORE | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-GOOR | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-GOGO | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-GOGR | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-GOAQ | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-GRRE | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-GROR | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-GRGO | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-GRGR | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-GRAQ | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-AQRE | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-AQOR | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-AQGO | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-AQGR | 20 (40 μL) | 200 μL |
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| C2CD2L-DDX10-20-AQAQ | 20 (40 μL) | 200 μL |
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DDX10 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies. [provided by RefSeq, Jul 2008]
Gene Name: DEAD-box Helicase 10
Chromosome: CHR11: 108535815 -108811648
Locus: 11q22.3
C2CD2L Gene Summary
The C2CD2 Like (C2CD2L) gene is located on chr11 :118978092-118987827 at 11q23.3.
Gene Name: C2CD2 Like
Chromosome: CHR11: 118978092 -118987827
Locus: 11q23.3
Gene Diseases
The C2CD2L DDX10 Fusion has been associated with the following diseases:
| Disease Name |
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| Acute Myeloid Leukemia |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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