C20ORF94-MKKS Fusion FISH Probe
The C20ORF94-MKKS Fusion FISH Probe is used to confirm a fusion of the C20ORF94 and MKKS genes. The fusion of the C20ORF94 and MKKS genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C20ORF94-MKKS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-RERE | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-REOR | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-REGO | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-REGR | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-REAQ | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-ORRE | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-OROR | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-ORGO | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-ORAQ | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-GORE | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-GOOR | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-GOGO | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-GOGR | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-GOAQ | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-GRRE | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-GROR | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-GRGO | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-GRGR | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-GRAQ | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-AQRE | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-AQOR | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-AQGO | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-AQGR | 20 (40 μL) | 200 μL |
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| C20ORF94-MKKS-20-AQAQ | 20 (40 μL) | 200 μL |
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MKKS Gene Summary
This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Name: McKusick-Kaufman Syndrome
Chromosome: CHR20: 10385832 -10414866
Locus: 20p12.2
Gene Diseases
The C20ORF94 MKKS Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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