C1QA-CD74 Fusion FISH Probe
The C1QA-CD74 Fusion FISH Probe is used to confirm a fusion of the C1QA and CD74 genes. The fusion of the C1QA and CD74 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C1QA-CD74-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-RERE | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-REOR | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-REGO | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-REGR | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-REAQ | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-ORRE | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-OROR | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-ORGO | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-ORAQ | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-GORE | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-GOOR | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-GOGO | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-GOGR | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-GOAQ | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-GRRE | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-GROR | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-GRGO | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-GRGR | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-GRAQ | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-AQRE | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-AQOR | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-AQGO | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-AQGR | 20 (40 μL) | 200 μL |
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| C1QA-CD74-20-AQAQ | 20 (40 μL) | 200 μL |
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C1QA Gene Summary
This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Gene Name: Complement C1q A Chain
Chromosome: CHR1: 22963117 -22966175
Locus: 1p36.12
CD74 Gene Summary
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Name: CD74 Molecule
Chromosome: CHR5: 149781199 -149792499
Locus: 5q33.1
Gene Diseases
The C1QA CD74 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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