C19ORF20-PRKACA Fusion FISH Probe
The C19ORF20-PRKACA Fusion FISH Probe is used to confirm a fusion of the C19ORF20 and PRKACA genes. The fusion of the C19ORF20 and PRKACA genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C19ORF20-PRKACA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-RERE | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-REOR | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-REGO | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-REGR | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-REAQ | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-ORRE | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-OROR | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-ORGO | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-ORAQ | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-GORE | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-GOOR | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-GOGO | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-GOGR | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-GOAQ | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-GRRE | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-GROR | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-GRGO | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-GRGR | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-GRAQ | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-AQRE | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-AQOR | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-AQGO | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-AQGR | 20 (40 μL) | 200 μL |
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| C19ORF20-PRKACA-20-AQAQ | 20 (40 μL) | 200 μL |
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PRKACA Gene Summary
This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms. [provided by RefSeq, Jan 2015]
Gene Name: Protein Kinase CAMP-activated Catalytic Subunit Alpha
Chromosome: CHR19: 14202506 -14228559
Locus: 19p13.12
Gene Diseases
The C19ORF20 PRKACA Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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