SEARCH OUR PRODUCT CATALOG

C12ORF66-NXF3 Fusion FISH Probe

The C12ORF66-NXF3 Fusion FISH Probe is used to confirm a fusion of the C12ORF66 and NXF3 genes. The fusion of the C12ORF66 and NXF3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
C12ORF66-NXF3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
C12ORF66-NXF3-20-RERE 20 (40 μL) 200 μL
C12ORF66-NXF3-20-REOR 20 (40 μL) 200 μL
C12ORF66-NXF3-20-REGO 20 (40 μL) 200 μL
C12ORF66-NXF3-20-REGR 20 (40 μL) 200 μL
C12ORF66-NXF3-20-REAQ 20 (40 μL) 200 μL
C12ORF66-NXF3-20-ORRE 20 (40 μL) 200 μL
C12ORF66-NXF3-20-OROR 20 (40 μL) 200 μL
C12ORF66-NXF3-20-ORGO 20 (40 μL) 200 μL
C12ORF66-NXF3-20-ORAQ 20 (40 μL) 200 μL
C12ORF66-NXF3-20-GORE 20 (40 μL) 200 μL
C12ORF66-NXF3-20-GOOR 20 (40 μL) 200 μL
C12ORF66-NXF3-20-GOGO 20 (40 μL) 200 μL
C12ORF66-NXF3-20-GOGR 20 (40 μL) 200 μL
C12ORF66-NXF3-20-GOAQ 20 (40 μL) 200 μL
C12ORF66-NXF3-20-GRRE 20 (40 μL) 200 μL
C12ORF66-NXF3-20-GROR 20 (40 μL) 200 μL
C12ORF66-NXF3-20-GRGO 20 (40 μL) 200 μL
C12ORF66-NXF3-20-GRGR 20 (40 μL) 200 μL
C12ORF66-NXF3-20-GRAQ 20 (40 μL) 200 μL
C12ORF66-NXF3-20-AQRE 20 (40 μL) 200 μL
C12ORF66-NXF3-20-AQOR 20 (40 μL) 200 μL
C12ORF66-NXF3-20-AQGO 20 (40 μL) 200 μL
C12ORF66-NXF3-20-AQGR 20 (40 μL) 200 μL
C12ORF66-NXF3-20-AQAQ 20 (40 μL) 200 μL

NXF3 Gene Summary

This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008]

Gene Name: Nuclear RNA Export Factor 3

Chromosome: CHRX: 102330749 -102348022

Locus: Xq22.1

C12orf66 Gene Summary

The Chromosome 12 Open Reading Frame 66 (C12orf66) gene is located on chr12 :64586418-64616076 at 12q14.2.

Gene Name: Chromosome 12 Open Reading Frame 66

Chromosome: CHR12: 64586418 -64616076

Locus: 12q14.2

Gene Diseases

The C12ORF66 NXF3 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.