C12ORF65-SLC11A2 Fusion FISH Probe
The C12ORF65-SLC11A2 Fusion FISH Probe is used to confirm a fusion of the C12ORF65 and SLC11A2 genes. The fusion of the C12ORF65 and SLC11A2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C12ORF65-SLC11A2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-RERE | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-REOR | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-REGO | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-REGR | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-REAQ | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-ORRE | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-OROR | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-ORGO | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-ORAQ | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-GORE | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-GOOR | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-GOGO | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-GOGR | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-GOAQ | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-GRRE | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-GROR | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-GRGO | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-GRGR | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-GRAQ | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-AQRE | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-AQOR | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-AQGO | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-AQGR | 20 (40 μL) | 200 μL |
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| C12ORF65-SLC11A2-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC11A2 Gene Summary
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]
Gene Name: Solute Carrier Family 11 Member 2
Chromosome: CHR12: 51373565 -51420199
Locus: 12q13.12
C12orf65 Gene Summary
This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Gene Name: Chromosome 12 Open Reading Frame 65
Chromosome: CHR12: 123717843 -123742506
Locus: 12q24.31
Gene Diseases
The C12ORF65 SLC11A2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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