C11ORF49-F2 Fusion FISH Probe
The C11ORF49-F2 Fusion FISH Probe is used to confirm a fusion of the C11ORF49 and F2 genes. The fusion of the C11ORF49 and F2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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C11ORF49-F2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-RERE | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-REOR | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-REGO | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-REGR | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-REAQ | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-ORRE | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-OROR | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-ORGO | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-ORAQ | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-GORE | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-GOOR | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-GOGO | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-GOGR | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-GOAQ | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-GRRE | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-GROR | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-GRGO | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-GRGR | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-GRAQ | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-AQRE | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-AQOR | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-AQGO | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-AQGR | 20 (40 μL) | 200 μL | ||
C11ORF49-F2-20-AQAQ | 20 (40 μL) | 200 μL |
F2 Gene Summary
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Gene Name: Coagulation Factor II, Thrombin
Chromosome: CHR11: 46740742 -46761056
Locus: 11p11.2
C11orf49 Gene Summary
The Chromosome 11 Open Reading Frame 49 (C11orf49) gene is located on chr11 :46958250-47185931 at 11p11.2.
Gene Name: Chromosome 11 Open Reading Frame 49
Chromosome: CHR11: 46958250 -47185931
Locus: 11p11.2
Gene Diseases
The C11ORF49 F2 Fusion has been associated with the following diseases:
Disease Name |
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Lung Adenocarcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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