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C11ORF49-F2 Fusion FISH Probe

The C11ORF49-F2 Fusion FISH Probe is used to confirm a fusion of the C11ORF49 and F2 genes. The fusion of the C11ORF49 and F2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
C11ORF49-F2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
C11ORF49-F2-20-RERE 20 (40 μL) 200 μL
C11ORF49-F2-20-REOR 20 (40 μL) 200 μL
C11ORF49-F2-20-REGO 20 (40 μL) 200 μL
C11ORF49-F2-20-REGR 20 (40 μL) 200 μL
C11ORF49-F2-20-REAQ 20 (40 μL) 200 μL
C11ORF49-F2-20-ORRE 20 (40 μL) 200 μL
C11ORF49-F2-20-OROR 20 (40 μL) 200 μL
C11ORF49-F2-20-ORGO 20 (40 μL) 200 μL
C11ORF49-F2-20-ORAQ 20 (40 μL) 200 μL
C11ORF49-F2-20-GORE 20 (40 μL) 200 μL
C11ORF49-F2-20-GOOR 20 (40 μL) 200 μL
C11ORF49-F2-20-GOGO 20 (40 μL) 200 μL
C11ORF49-F2-20-GOGR 20 (40 μL) 200 μL
C11ORF49-F2-20-GOAQ 20 (40 μL) 200 μL
C11ORF49-F2-20-GRRE 20 (40 μL) 200 μL
C11ORF49-F2-20-GROR 20 (40 μL) 200 μL
C11ORF49-F2-20-GRGO 20 (40 μL) 200 μL
C11ORF49-F2-20-GRGR 20 (40 μL) 200 μL
C11ORF49-F2-20-GRAQ 20 (40 μL) 200 μL
C11ORF49-F2-20-AQRE 20 (40 μL) 200 μL
C11ORF49-F2-20-AQOR 20 (40 μL) 200 μL
C11ORF49-F2-20-AQGO 20 (40 μL) 200 μL
C11ORF49-F2-20-AQGR 20 (40 μL) 200 μL
C11ORF49-F2-20-AQAQ 20 (40 μL) 200 μL

F2 Gene Summary

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Gene Name: Coagulation Factor II, Thrombin

Chromosome: CHR11: 46740742 -46761056

Locus: 11p11.2

C11orf49 Gene Summary

The Chromosome 11 Open Reading Frame 49 (C11orf49) gene is located on chr11 :46958250-47185931 at 11p11.2.

Gene Name: Chromosome 11 Open Reading Frame 49

Chromosome: CHR11: 46958250 -47185931

Locus: 11p11.2

Gene Diseases

The C11ORF49 F2 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.