C11ORF48-BSCL2 Fusion FISH Probe
The C11ORF48-BSCL2 Fusion FISH Probe is used to confirm a fusion of the C11ORF48 and BSCL2 genes. The fusion of the C11ORF48 and BSCL2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C11ORF48-BSCL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-RERE | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-REOR | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-REGO | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-REGR | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-REAQ | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-ORRE | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-OROR | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-ORGO | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-GORE | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-GOOR | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-GOGO | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-GOGR | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-GRRE | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-GROR | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-GRGO | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-GRGR | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-AQRE | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-AQOR | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-AQGO | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-AQGR | 20 (40 μL) | 200 μL |
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| C11ORF48-BSCL2-20-AQAQ | 20 (40 μL) | 200 μL |
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BSCL2 Gene Summary
This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).[provided by RefSeq, Mar 2011]
Gene Name: BSCL2, Seipin Lipid Droplet Biogenesis Associated
Chromosome: CHR11: 62457733 -62477091
Locus: 11q12.3
Gene Diseases
The C11ORF48 BSCL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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