C10ORF18-ABI1 Fusion FISH Probe
The C10ORF18-ABI1 Fusion FISH Probe is used to confirm a fusion of the C10ORF18 and ABI1 genes. The fusion of the C10ORF18 and ABI1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C10ORF18-ABI1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-RERE | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-REOR | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-REGO | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-REGR | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-REAQ | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-ORRE | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-OROR | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-ORGO | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-ORAQ | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-GORE | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-GOOR | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-GOGO | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-GOGR | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-GOAQ | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-GRRE | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-GROR | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-GRGO | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-GRGR | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-GRAQ | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-AQRE | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-AQOR | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-AQGO | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-AQGR | 20 (40 μL) | 200 μL |
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| C10ORF18-ABI1-20-AQAQ | 20 (40 μL) | 200 μL |
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ABI1 Gene Summary
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
Gene Name: Abl Interactor 1
Chromosome: CHR10: 27035524 -27150016
Locus: 10p12.1
Gene Diseases
The C10ORF18 ABI1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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