BTN3A2-HIST1H2AC Fusion FISH Probe
The BTN3A2-HIST1H2AC Fusion FISH Probe is used to confirm a fusion of the BTN3A2 and HIST1H2AC genes. The fusion of the BTN3A2 and HIST1H2AC genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BTN3A2-HIST1H2AC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-RERE | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-REOR | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-REGO | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-REGR | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-REAQ | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-ORRE | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-OROR | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-ORGO | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-ORAQ | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-GORE | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-GOOR | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-GOGO | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-GOGR | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-GOAQ | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-GRRE | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-GROR | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-GRGO | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-GRGR | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-GRAQ | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-AQRE | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-AQOR | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-AQGO | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-AQGR | 20 (40 μL) | 200 μL |
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| BTN3A2-HIST1H2AC-20-AQAQ | 20 (40 μL) | 200 μL |
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HIST1H2AC Gene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
Gene Name: Histone Cluster 1 H2A Family Member C
Chromosome: CHR6: 26124372 -26124918
Locus: 6p22.2
BTN3A2 Gene Summary
This gene encodes a member of the immunoglobulin superfamily, which resides in the juxta-telomeric region of the major histocompatability class 1 locus and is clustered with the other family members on chromosome 6. The encoded protein may be involved in the adaptive immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
Gene Name: Butyrophilin Subfamily 3 Member A2
Chromosome: CHR6: 26365397 -26378548
Locus: 6p22.2
Gene Diseases
The BTN3A2 HIST1H2AC Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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