BSPRY-NPM1 Fusion FISH Probe
The BSPRY-NPM1 Fusion FISH Probe is used to confirm a fusion of the BSPRY and NPM1 genes. The fusion of the BSPRY and NPM1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BSPRY-NPM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-RERE | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-REOR | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-REGO | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-REGR | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-REAQ | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-ORRE | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-OROR | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-ORGO | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-GORE | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-GOOR | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-GOGO | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-GOGR | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-GRRE | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-GROR | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-GRGO | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-GRGR | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-AQRE | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-AQOR | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-AQGO | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-AQGR | 20 (40 μL) | 200 μL |
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| BSPRY-NPM1-20-AQAQ | 20 (40 μL) | 200 μL |
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NPM1 Gene Summary
The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
Gene Name: Nucleophosmin 1
Chromosome: CHR5: 170814707 -170837888
Locus: 5q35.1
BSPRY Gene Summary
The B-box And SPRY Domain Containing (BSPRY) gene is located on chr9 :116111811-116133513 at 9q32.
Gene Name: B-box And SPRY Domain Containing
Chromosome: CHR9: 116111811 -116133513
Locus: 9q32
Gene Diseases
The BSPRY NPM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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