BRWD3-LRCH2 Fusion FISH Probe
The BRWD3-LRCH2 Fusion FISH Probe is used to confirm a fusion of the BRWD3 and LRCH2 genes. The fusion of the BRWD3 and LRCH2 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BRWD3-LRCH2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| BRWD3-LRCH2-20-AQAQ | 20 (40 μL) | 200 μL |
|
LRCH2 Gene Summary
This gene encodes a member of the leucine-rich repeat and calponin homology domain-containing protein family. These family members contain multiple N-terminal leucine-rich repeats, in addition to a C-terminal calponin homology domain, a type of domain that mediates interactions with actin filaments. These proteins are conserved across animal species, and studies of a similar Drosophila protein indicate a function as a cytoskeletal scaffolding protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Gene Name: Leucine Rich Repeats And Calponin Homology Domain Containing 2
Chromosome: CHRX: 114345182 -114468635
Locus: Xq23
BRWD3 Gene Summary
The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene are associated with a spectrum of cognitive disabilities and X-linked macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, Jul 2017]
Gene Name: Bromodomain And WD Repeat Domain Containing 3
Chromosome: CHRX: 79924986 -80065233
Locus: Xq21.1
Gene Diseases
The BRWD3 LRCH2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|