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BPTF-BCAS3 Fusion FISH Probe

The BPTF-BCAS3 Fusion FISH Probe is used to confirm a fusion of the BPTF and BCAS3 genes. The fusion of the BPTF and BCAS3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BPTF-BCAS3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
BPTF-BCAS3-20-RERE 20 (40 μL) 200 μL
BPTF-BCAS3-20-REOR 20 (40 μL) 200 μL
BPTF-BCAS3-20-REGO 20 (40 μL) 200 μL
BPTF-BCAS3-20-REGR 20 (40 μL) 200 μL
BPTF-BCAS3-20-REAQ 20 (40 μL) 200 μL
BPTF-BCAS3-20-ORRE 20 (40 μL) 200 μL
BPTF-BCAS3-20-OROR 20 (40 μL) 200 μL
BPTF-BCAS3-20-ORGO 20 (40 μL) 200 μL
BPTF-BCAS3-20-ORAQ 20 (40 μL) 200 μL
BPTF-BCAS3-20-GORE 20 (40 μL) 200 μL
BPTF-BCAS3-20-GOOR 20 (40 μL) 200 μL
BPTF-BCAS3-20-GOGO 20 (40 μL) 200 μL
BPTF-BCAS3-20-GOGR 20 (40 μL) 200 μL
BPTF-BCAS3-20-GOAQ 20 (40 μL) 200 μL
BPTF-BCAS3-20-GRRE 20 (40 μL) 200 μL
BPTF-BCAS3-20-GROR 20 (40 μL) 200 μL
BPTF-BCAS3-20-GRGO 20 (40 μL) 200 μL
BPTF-BCAS3-20-GRGR 20 (40 μL) 200 μL
BPTF-BCAS3-20-GRAQ 20 (40 μL) 200 μL
BPTF-BCAS3-20-AQRE 20 (40 μL) 200 μL
BPTF-BCAS3-20-AQOR 20 (40 μL) 200 μL
BPTF-BCAS3-20-AQGO 20 (40 μL) 200 μL
BPTF-BCAS3-20-AQGR 20 (40 μL) 200 μL
BPTF-BCAS3-20-AQAQ 20 (40 μL) 200 μL

BPTF Gene Summary

This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex. In Drosophila, the NURF complex, which catalyzes nucleosome sliding on DNA and interacts with sequence-specific transcription factors, is necessary for the chromatin remodeling required for transcription. Two alternative transcripts encoding different isoforms have been described completely. [provided by RefSeq, Jul 2008]

Gene Name: Bromodomain PHD Finger Transcription Factor

Chromosome: CHR17: 65821779 -65980494

Locus: 17q24.2

BCAS3 Gene Summary

The BCAS3, Microtubule Associated Cell Migration Factor (BCAS3) gene is located on chr17 :58755171-59470199 at 17q23.2.

Gene Name: BCAS3, Microtubule Associated Cell Migration Factor

Chromosome: CHR17: 58755171 -59470199

Locus: 17q23.2

Gene Diseases

The BPTF BCAS3 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.