BMP7-RBM38 Fusion FISH Probe
The BMP7-RBM38 Fusion FISH Probe is used to confirm a fusion of the BMP7 and RBM38 genes. The fusion of the BMP7 and RBM38 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BMP7-RBM38-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-RERE | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-REOR | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-REGO | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-REGR | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-REAQ | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-ORRE | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-OROR | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-ORGO | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-ORAQ | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-GORE | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-GOOR | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-GOGO | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-GOGR | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-GOAQ | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-GRRE | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-GROR | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-GRGO | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-GRGR | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-GRAQ | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-AQRE | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-AQOR | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-AQGO | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-AQGR | 20 (40 μL) | 200 μL |
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| BMP7-RBM38-20-AQAQ | 20 (40 μL) | 200 μL |
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BMP7 Gene Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]
Gene Name: Bone Morphogenetic Protein 7
Chromosome: CHR20: 55743808 -55841707
Locus: 20q13.31
RBM38 Gene Summary
The RNA Binding Motif Protein 38 (RBM38) gene is located on chr20 :55966453-55984386 at 20q13.31.
Gene Name: RNA Binding Motif Protein 38
Chromosome: CHR20: 55966453 -55984386
Locus: 20q13.31
Gene Diseases
The BMP7 RBM38 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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