BMP7-MACROD2 Fusion FISH Probe
The BMP7-MACROD2 Fusion FISH Probe is used to confirm a fusion of the BMP7 and MACROD2 genes. The fusion of the BMP7 and MACROD2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BMP7-MACROD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| BMP7-MACROD2-20-AQAQ | 20 (40 μL) | 200 μL |
|
BMP7 Gene Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]
Gene Name: Bone Morphogenetic Protein 7
Chromosome: CHR20: 55743808 -55841707
Locus: 20q13.31
MACROD2 Gene Summary
The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage. [provided by RefSeq, May 2017]
Gene Name: MACRO Domain Containing 2
Chromosome: CHR20: 13976145 -16033841
Locus: 20p12.1
Gene Diseases
The BMP7 MACROD2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|