BMP2K-SHROOM3 Fusion FISH Probe
The BMP2K-SHROOM3 Fusion FISH Probe is used to confirm a fusion of the BMP2K and SHROOM3 genes. The fusion of the BMP2K and SHROOM3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BMP2K-SHROOM3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-RERE | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-REOR | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-REGO | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-REGR | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-REAQ | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-ORRE | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-OROR | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-ORGO | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-ORAQ | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-GORE | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-GOOR | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-GOGO | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-GOGR | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-GOAQ | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-GRRE | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-GROR | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-GRGO | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-GRGR | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-GRAQ | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-AQRE | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-AQOR | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-AQGO | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-AQGR | 20 (40 μL) | 200 μL |
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| BMP2K-SHROOM3-20-AQAQ | 20 (40 μL) | 200 μL |
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BMP2K Gene Summary
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: BMP2 Inducible Kinase
Chromosome: CHR4: 79697531 -79833341
Locus: 4q21.21
SHROOM3 Gene Summary
This gene encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues. A similar protein in mice is required for proper neurulation. [provided by RefSeq, Jan 2011]
Gene Name: Shroom Family Member 3
Chromosome: CHR4: 77356252 -77704405
Locus: 4q21.1
Gene Diseases
The BMP2K SHROOM3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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