BLNK-PIK3AP1 Fusion FISH Probe
The BLNK-PIK3AP1 Fusion FISH Probe is used to confirm a fusion of the BLNK and PIK3AP1 genes. The fusion of the BLNK and PIK3AP1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BLNK-PIK3AP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| BLNK-PIK3AP1-20-AQAQ | 20 (40 μL) | 200 μL |
|
BLNK Gene Summary
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
Gene Name: B-cell Linker
Chromosome: CHR10: 97951454 -98031333
Locus: 10q24.1
PIK3AP1 Gene Summary
The Phosphoinositide-3-kinase Adaptor Protein 1 (PIK3AP1) gene is located on chr10 :98353068-98480279 at 10q24.1.
Gene Name: Phosphoinositide-3-kinase Adaptor Protein 1
Chromosome: CHR10: 98353068 -98480279
Locus: 10q24.1
Gene Diseases
The BLNK PIK3AP1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|