BLMH-ABCA9 Fusion FISH Probe
The BLMH-ABCA9 Fusion FISH Probe is used to confirm a fusion of the BLMH and ABCA9 genes. The fusion of the BLMH and ABCA9 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BLMH-ABCA9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-RERE | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-REOR | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-REGO | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-REGR | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-REAQ | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-ORRE | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-OROR | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-ORGO | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-ORAQ | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-GORE | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-GOOR | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-GOGO | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-GOGR | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-GOAQ | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-GRRE | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-GROR | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-GRGO | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-GRGR | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-GRAQ | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-AQRE | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-AQOR | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-AQGO | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-AQGR | 20 (40 μL) | 200 μL |
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| BLMH-ABCA9-20-AQAQ | 20 (40 μL) | 200 μL |
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BLMH Gene Summary
Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008]
Gene Name: Bleomycin Hydrolase
Chromosome: CHR17: 28575212 -28619184
Locus: 17q11.2
ABCA9 Gene Summary
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily A Member 9
Chromosome: CHR17: 66970772 -67057136
Locus: 17q24.2
Gene Diseases
The BLMH ABCA9 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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