BLM-ABHD2 Fusion FISH Probe
The BLM-ABHD2 Fusion FISH Probe is used to confirm a fusion of the BLM and ABHD2 genes. The fusion of the BLM and ABHD2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BLM-ABHD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| BLM-ABHD2-20-AQAQ | 20 (40 μL) | 200 μL |
|
BLM Gene Summary
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008]
Gene Name: Bloom Syndrome RecQ Like Helicase
Chromosome: CHR15: 91260578 -91358686
Locus: 15q26.1
ABHD2 Gene Summary
This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a wide range of enzymes. The encoded protein is an acylglycerol lipase that catalyzes the hydrolysis of endocannabinoid arachidonoylglycerol from the cell membrane. This leads to activation of the sperm calcium channel CatSper, which results in sperm activation. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jan 2017]
Gene Name: Abhydrolase Domain Containing 2
Chromosome: CHR15: 89631380 -89745591
Locus: 15q26.1
Gene Diseases
The BLM ABHD2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|