BIRC2-YAP1 Fusion FISH Probe
The BIRC2-YAP1 Fusion FISH Probe is used to confirm a fusion of the BIRC2 and YAP1 genes. The fusion of the BIRC2 and YAP1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BIRC2-YAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-RERE | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-REOR | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-REGO | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-REGR | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-OROR | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-GORE | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-GROR | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| BIRC2-YAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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BIRC2 Gene Summary
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Baculoviral IAP Repeat Containing 2
Chromosome: CHR11: 102217965 -102249401
Locus: 11q22.2
YAP1 Gene Summary
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Gene Name: Yes Associated Protein 1
Chromosome: CHR11: 101981191 -102104154
Locus: 11q22.1
Gene Diseases
The BIRC2 YAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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