BICD1-DENND5B Fusion FISH Probe
The BICD1-DENND5B Fusion FISH Probe is used to confirm a fusion of the BICD1 and DENND5B genes. The fusion of the BICD1 and DENND5B genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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BICD1-DENND5B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-RERE | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-REOR | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-REGO | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-REGR | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-REAQ | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-ORRE | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-OROR | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-ORGO | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-ORAQ | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-GORE | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-GOOR | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-GOGO | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-GOGR | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-GOAQ | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-GRRE | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-GROR | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-GRGO | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-GRGR | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-GRAQ | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-AQRE | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-AQOR | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-AQGO | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-AQGR | 20 (40 μL) | 200 μL | ||
BICD1-DENND5B-20-AQAQ | 20 (40 μL) | 200 μL |
BICD1 Gene Summary
This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema. [provided by RefSeq, Aug 2017]
Gene Name: BICD Cargo Adaptor 1
Chromosome: CHR12: 32260184 -32531141
Locus: 12p11.21
DENND5B Gene Summary
The DENN Domain Containing 5B (DENND5B) gene is located on chr12 :31535156-31743952 at 12p11.21.
Gene Name: DENN Domain Containing 5B
Chromosome: CHR12: 31535156 -31743952
Locus: 12p11.21
Gene Diseases
The BICD1 DENND5B Fusion has been associated with the following diseases:
Disease Name |
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Liver Hepatocellular Carcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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